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December 7, 2017 | 11:00 a.m. - 12:00 p.m.
Category: Seminar
Location: Scott Hall #3125 | Map
540 E. Canfield
Detroit, MI 48201
Cost: Free
Audience: Current Graduate Students, Faculty

Seminars in Translational Biomedicine

Vaibhav A. Diwadkar, PhD

Professor of Psychiatry & Behavioral Neurosciences, Co-Director of the Brain Imaging Research Division, Wayne State University School of Medicine

“The brain’s macro-networks and their relevance for medicine: Explorations in neuropsychiatry”

ABSTRACT

Neuropsychiatric conditions like schizophrenia are revealed through the patient's behavior, and the most compelling “causal” pre-cursor for behavior is brain function. Yet, our understanding of brain-behavior relationships is rudimentary at best, consequently hindering understanding of the bases of illnesses like schizophrenia. Furthermore, the ease of human functional MRI (fMRI) has led to a surfeit of published studies that produce prodigious numbers of results without adequately elaborating on putative mechanisms. This frequently adds confusion and amplifies lack of understanding.

In this talk, I will elaborate on several approaches using fMRI that can provide putative mechanistic understanding of how macro-networks in the brain underlie behavior. By extension this approach can illuminate how brain network dysfunction contributes to the risk for and the emergence of both Axis I and II neuropsychiatric disorders including schizophrenia, borderline personality disorder and obsessive compulsive disorder.

To be relevant for medicine, fMRI will have to demonstrate its viability in providing some measure of foundational understanding about neurobiological phenomenon. Thus, this talk will emphasize the methods value as an incremental (as opposed to transformational) tool for understanding aspects of brain network function and dysfunction.

For more information about this event, please contact Suzanne Shaw at 577-5325 or sshaw@wayne.edu.