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March 19, 2019 | 12:00 p.m. - 1:00 p.m.
Category: Seminar
Location: Integrative Biosciences Center IBio Conference Center | Map
6135 Woodward Ave.
Detroit , MI 48202
Cost: Free
Audience: Academic Staff, Alumni, Community, Current Graduate Students, Current Undergraduate Students, Staff

The Campus Community is invited to a research seminar  

Metabolic Modulation is a Strategy to Limit Ischemic Insults in Aging

hosted by

the Departments of Pathology, Physiology, and Ophthalmology, Visual & Anatomical Sciences


The Office of the Vice President for Research

with guest speaker, Ji Li, Ph.D.

Associate Professor, Physiology and Biophysics

University of Mississippi Medical Center

March 19, 2019

12 noon to 1 p.m.

IBio Conference Center

The Wayne State University community is invited to attend a research  presentation with guest speaker, Ji Li, Ph.D., associate professor from the Department of Physiology and Biophysics at the University of Mississippi Medical Center.

The presentation will be held on March 19, 2019 at 12:00 noon in the first floor seminar room of IBio, located at 6135 Woodward. The seminar is free and open to the entire university community. 

Dr. Li will present, "Metabolic Modulation is a Strategy to Limit Ischemic Insults in Aging."

Dr. Li earned his B.S. degree in biochemistry at Lanzhou University and a Ph.D. in in Cell Biology at Lanzhou University. 


Ischemic heart disease contributes to the leading cause of morbidity and mortality in the elderly. This lecture will clarify a critical function of novel stress-inducible protein Sestrin2 in controlling the energy sensor AMP-activated protein kinase (AMPK) signaling and reveal the molecular network underlying the regulation of Sestrin2-AMPK signaling pathways in aging; especially focusing on the modulation of glucose transporter trafficking by Sestrin2-AMPK signaling. The lecture goal is providing a novel rationale for treatment and prevention of age-related ischemic heart disease using beneficial metabolic activities of Sestrin2-AMPK signaling cascades.  The outcome of this research work may pave the way for novel drugs to be developed that effectively and specifically target the specific pathway for use in combating myocardial dysfunction in the elderly.

We hope you can join us for this interesting seminar!  

For more information about this event, please contact Julie O'Connor at 3135775600 or