Lipids@Wayne Seminar: Christine Keating, "Lipid membranes in and around aqueous multiphase systems"
This event is in the past.
Detroit, MI 48202
All are welcome to attend our biweekly the Lipids@Wayne seminar. Pizza will be served.
Speaker: Prof. Christine Keating, Professor of Chemistry, Penn State University
Title: Lipid membranes in and around aqueous multiphase systems
Location: 1167 Biological Sciences
Date and Time: 4 pm on Wednesday, November 6, 2019
Abstract: Living cells take advantage of both lipid membranes and liquid-liquid phase separation to organize their interior volumes. The resulting membrane-bound and membraneless organelles provide regions with different molecular composition, physical properties, and reactivity. This compartmentalization is crucial to cellular function. In some cases, it appears that these two intracellular compartment types may be interacting in vivo to perform their biological functions, for example in signaling and intracellular communication. Simple experimental models for both types of compartments can be generated in vitro, but few studies have yet been done in which both types of assemblies were present together. This presentation will discuss experiments in which lipid assemblies (vesicles, membranes) and aqueous multiphase systems coexist, and will explore ways in which these compartmentalization motifs interact. Such studies can provide fundamental insights into principles underlying biological organization and could lead to greater functionality in artificial cells assembled from the bottom up.