CMMG Seminar Series

Thursday, June 11, 2026

11:00 a.m. in 2268 Scott Hall

Qing Lin, MD, PhD

Associate Professor, Department of Surgery, Division of Cardiac Surgery, The Ohio State University, College of Medicine

Host: Li Li, PhD

“Innate Immune Cells in Wound Healing”

Abstract

Tissue injury triggers innate immune responses that are essential for host defense and tissue repair. However, dysregulated inflammation can lead to pathological outcomes such as fibrosis and abnormal angiogenesis. Our laboratory studies how innate immune cells regulate wound healing in the skin, eye, and lung, three organs that share epithelial barrier features while also possessing unique structural and functional characteristics.

In this seminar, I will discuss wound healing in these three organs, highlighting both their similarities and differences from an immunoregulatory perspective. Specifically, the talk will focus on the roles of innate immune cells, including mast cells, neutrophils, and macrophages, and how their phenotypic and functional plasticity influences tissue remodeling in these organs. This work highlights how immune cells shape healing outcomes and could inform new immunotherapeutic strategies to promote regeneration while preventing fibrosis and pathological angiogenesis.