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College of Engineering

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September 12, 2017 | 2:30 p.m. - 3:20 p.m.
Category: Seminar
Location: Engineering, College of #1507 | Map
5050 Anthony Wayne
Detroit, MI 48202
Cost: Free
Audience: Academic Staff, Current Graduate Students, Current Undergraduate Students, Faculty
Biomaterials in the Brain: Key Initiatives to Improve Brain-device Interactions in the Treatment of Hydrocephalus

Speaker: Professor Carolyn Harris, Department of Chemical Engineering and Materials Science, Wayne State University
Nearly all biomaterials become engulfed by the foreign body response, an inflammatory response that attempts to wall off any device to protect the host from foreign materials. In the treatment of neurological disorders, like in the treatment of hydrocephalus, shunts fail in a similar way. In fact, shunts fail more often than any other neurological device requiring patients to undergo multiple if not dozens of shunt revisions in their lifetime. Despite our efforts for 60 years, 98% of all shunts fail after ten years.
By integrating quantitative big-data analysis of the cells and tissues that cause shunts to fail, real-time analyses of patient data, and innovative concepts tested in novel in vitro bioreactors, Dr. Harris and her research team have begun piecing together how and why shunts fail. The collaborative team of engineers, neurosurgeons, students, and small businesses collaborators is actively seeking strategies to remediate shunt failure using these identified mechanisms of shunt failure.
For more information about this event, please contact Guangzhao Mao at 313-577-3800 or