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May 4, 2017 | 12:30 p.m. - 1:30 p.m.
Category: Seminar
Location: Integrative Biosciences Center IBio Conference Room 1D | Map
6135 Woodward Ave.
Detroit , MI 48202
Cost: Free
Audience: Community, Current Graduate Students, Current Undergraduate Students, Faculty

The Center for Urban Responses to Environmental Stressors (CURES) and Integrative Biosciences
Presents their Thursday Afternoon Seminar Series
May 4, 2017 from 12:30 to 1:30 p.m.
Seminar Room 1D, IBio Building, located at 6135 Woodward Ave.

The guest speaker will be R. Thomas Zoeller, Ph.D., professor in the Department of Biology at the University of Massachusetts-Amherst. Dr. Zoeller will present, "Thyroid Hormone, Industrial Chemicals and Environmental Health."

Dr. Zoeller received his B.S., in biology from Indiana University, Bloomington, and his M.A. in Endocrinology and his Ph.D. in Neuroendocrinology from Oregon State University, Corvallis. 


Thyroid hormone is essential for brain development, but also throughout life. Clinical studies have demonstrated the sensitivity of the developing brain to thyroid hormone insufficiency. Molecular and experimental studies in animals have begun to reveal the mechanisms and developmental events regulated by thyroid hormone. New insights into general features of the regulation of thyroid hormone action at the tissue level indicates that some - and perhaps all - tissues have some autonomous control over thyroid hormone action, independent of changes in circulating levels of thyroid hormone. The importance of thyroid hormone in development and health requires careful scrutiny of chemicals in the environment that may cause adverse health effects by interfering with thyroid hormone action. Recent studies in this domain demonstrate that chemicals can have quite enigmatic effects on thyroid hormone action - effects that are not considered in the design of guideline studies in the U.S., OECD, or Japan. However, because these guideline studies are designed and approved by international committees, they are represented to the public as a “gold standard”. The goal of this lecture is to provide a synthesis of information from experimental, clinical and epidemiological studies to highlight the shortcomings of guideline approaches protecting public health from “thyroid disrupting” chemicals.

For more information about this event, please contact Julie O'Connor at 3135775600 or julie.oconnor@wayne.edu.