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November 3, 2017 | 8:00 a.m. - 4:45 p.m.
Category: Seminar
Location: Margherio Family Conference Center
320 E. Canfield
Detroit, MI 48202
Cost: Free
Audience: Academic Staff, Alumni, Current Graduate Students, Current Undergraduate Students, Faculty, Staff

The Wayne State University School of Medicine’s Department of Pharmacology, the School of Medicine and the Barbara Ann Karmanos Cancer Institute have developed a symposium in tribute to the longtime chair of Pharmacology, Bonnie Sloane, Ph.D.

Dr. Sloane, a WSU distinguished professor, chaired the Department of Pharmacology from 1995 until she stepped down from the position to continue conducting research in late 2015. From 1999 to 2005, she led the Karmanos Cancer Institute’s Proteases and Cancer Program.

A bibliometric analysis by the Council of Canadian Academies in 2011 identified Dr. Sloane as the corresponding author of one of the top 1% most highly cited papers in her field worldwide. In 2012, Dr. Sloane received the Pan-American Association for Biochemistry and Molecular Biology Plenary Lecturer Award during the 41st annual meeting of the Brazilian Biochemistry and Molecular Biology Society. That same year she received the WSU Outstanding Research Achievement Award, given to a faculty member in a basic science or clinical department who has made significant and career-long contributions to the advancement of an area of biomedical, behavioral, clinical or medical research. Dr. Sloane has been honored locally and nationally as a research mentor as an inaugural Wayne State University Outstanding Graduate Mentor and an inaugural mentor for the Avon Foundation/American Association of Cancer Research International Scholar in Breast Cancer Program. In addition, she has been the recipient of numerous awards from both Wayne State University and the School of Medicine, including the WSU Charles Gershenson Distinguished Faculty Fellow, WSU Academy of Scholars, KCI Heroes of Breast Cancer, and the Lawrence M. Wiener Award, from the WSU Medical Alumni Association.

Her work in the field of proteolysis research earned Dr. Sloane a Lifetime Membership Award for outstanding contributions from the International Proteolysis Society in 2010. She served as president of the organization from 1999 to 2001, and on its council from 2003 to 2007.

In addition to conducting her own proteolysis research, Dr. Sloane mentored many young researchers, including international scientists. One of her proteges, Mona Mostafa Mohamed, Ph.D., is now the director of Cairo University’s Cancer Biology Research Laboratory, which opened in 2009. Dr. Sloane served as her mentor and provided oversight for Dr. Mohamed’s inflammatory breast cancer research from 2005 to April 2007.

The day long international symposium, “Proteases in Cancer Biology and Other Diseases” is scheduled to take place from 8:00 a.m. to 4:30 p.m. Nov. 3, 2017. The agenda is as follows: 

8:00 am: Breakfast

8:30 am: Keith Whitfield, Provost, (WSU); Opening Remarks

8:40 am: Lynn Matrisian (Pancreatic Cancer Action Network) "Blind Men and Elephants: Looking at Cancer from Many Perspectives"

9:05 am: Barbara Fingleton (Vanderbilt University) "The IL-4 Receptor Promotes Breast Cancer and Colon Tumor Progression"

9:25 am: Matthew Bogyo (Stanford University) "Optimization of Cathepsin-Activated Probes for Optical Surgical Navigation"

9:50 am: Galia Blum (Hebrew University) "Protease Targeted Nano Particles for CT Imaging"
 
10:10 am: Morning Break
 
10:40 am: Margarete Heck (University of Edinburgh) "Where in the World Can a Protease Take You?"
 
11:05 am: Simon Hayward (NorthShore University HealthSystem Research Institute) "Stromal Heterogeneity, Inflammation, and Androgen Receptor Action in Prostate Cancer"
 
11:30 am: Tamara Lah (Slovenia National Institute of Biology) "Tumour Microenvironment Plays Crucial Role in Regulating Tumour Progression"
 
11:55 am: Lunch
 
1:00 pm: Presentation of Women in Medicine and Science Leadership Award to Dr. Bonnie Sloane by Dean Jack Sobel
 
1:15 pm: Izabela Podgorski (WSU) "Osteomacs and Bone Marrow Fat Cells: Key Regulators of Chemotherapeutic Response in Metastatic Prostate Cancer?"
 
1:35 pm: Wei-ping Ren (WSU) "3D Cell Culture in an Electrospun Nanofiber Sheet with Desired Microstructure"
 
1:55 pm: Dora Cavallo-Medved (University of Windsor) "Student-Faculty Partnerships in Cancer Research and Education"
 
2:15 pm: Jennifer Koblinski (Virginia Commonwealth University) "Syndecan-1 Regulation of IL-8 Signaling Mediates Breast Cancer Metastasis to the Brain Through Modulation of Blood Brain Barrier Permeability"
 
2:35 pm: Afternoon break

2:55 pm: Larry Matherly Associate Center Director for Basic Sciences (WSU); Introduction of the Keynote Speaker
 
3:00 pm: Klaudia Brix (Jacobs University, Bremen, Germany) Key Note- "Proteases Take Chances- Making Sense of Their Traveling Through and Beyond Cells"
 
4:00 pm: Ray Mattingly, Chair, Dept. of Pharmacology (WSU); Introduction of Bonnie Sloane
 
4:05 pm: Bonnie Sloane (WSU)  Closing Remarks
 
Breakfast and lunch are provided.
For more information about this event, please contact Linda Mayernik at 313-577-2511 or linda.mayernik@wayne.edu.