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April 4, 2018 | 1:00 p.m. - 2:00 p.m.
Category: Seminar
Location: Scott Hall #3125 | Map
540 E. Canfield
Detroit, MI 48201
Cost: Free
Audience: Current Graduate Students, Current Undergraduate Students, Faculty, Staff

11th Annual Henry L. Brasza Lecture in Diabetes

Mitchell A. Lazar, MD, PhD, the Willard and Rhoda Ware Professor in Diabetes and Metabolic Diseases, the Chief of the Division of Endocrinology, Diabetes, and Metabolism, and the Director of the Institute for Diabetes, Obesity, and Metabolism at the University of Pennsylvania, Member of the National Academy of Sciences

“Ups and Downs of Gene Transcription and Metabolism"


The epidemics of diabetes and obesity represent major challenges for modern societies.   Although these diseases have a strong genetic basis, their inexorable rise is principally due to the impact of environmental changes including fattening diets, insufficient physical activity, and exposure to light around the clock. These challenges overwhelm the normal physiological control of circadian rhythms and organismal homeostasis, in large part through dysregulation of gene transcription, leading to metabolic diseases. Recent work will be presented to highlight these principles and demonstrate the underlying mechanisms.


For more information about this event, please contact Suzanne Shaw at 577-5325 or